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Effects of P. distasonis gavage on intestinal cytokine levels in weaned piglets after ETEC challenge. ( A ) Relative mRNA expression levels of inflammatory cytokines ( TNF-α , IL-1β , IL-6 , IL-8 ) and anti-inflammatory cytokine ( IL-10 ) as well as interferon-γ ( IFN-γ ) in the ileum. ( B ) Concentrations of TNF-α, IL-1β, IL-6, IL-8, IL-10, and IFN-γ in the ileal mucosa. Data are presented as the Mean ± SME. “*”indicated 0.01 ≤ P ≤ 0.05, “**” indicated 0.001 ≤ P ≤ 0.01, and “***” indicated P ≤ 0.001

Journal: Porcine Health Management

Article Title: Parabacteroides distasonis ameliorates ETEC-induced diarrhea in weaned piglets by regulating intestinal barrier function and intestinal inflammation

doi: 10.1186/s40813-026-00525-1

Figure Lengend Snippet: Effects of P. distasonis gavage on intestinal cytokine levels in weaned piglets after ETEC challenge. ( A ) Relative mRNA expression levels of inflammatory cytokines ( TNF-α , IL-1β , IL-6 , IL-8 ) and anti-inflammatory cytokine ( IL-10 ) as well as interferon-γ ( IFN-γ ) in the ileum. ( B ) Concentrations of TNF-α, IL-1β, IL-6, IL-8, IL-10, and IFN-γ in the ileal mucosa. Data are presented as the Mean ± SME. “*”indicated 0.01 ≤ P ≤ 0.05, “**” indicated 0.001 ≤ P ≤ 0.01, and “***” indicated P ≤ 0.001

Article Snippet: For the quantification of cytokine levels in ileal mucosa, a commercial porcine cytokine multiplex immunoassay kit (RayBiotech, Norcross, GA, USA) was used, and cytokine concentrations were calculated using QAP-CYT-1-SW software (RayBiotech, Peachtree Corners, GA, USA).

Techniques: Expressing

No differences were observed in plasma NfL or GFAP across ages 18 to 30 between variant carriers and non-carriers of C9orf72, GRN, or MAPT .

Journal: medRxiv

Article Title: Trajectories of brain structure and function in young adult carriers of genetic frontotemporal dementia variants

doi: 10.64898/2026.06.08.26355165

Figure Lengend Snippet: No differences were observed in plasma NfL or GFAP across ages 18 to 30 between variant carriers and non-carriers of C9orf72, GRN, or MAPT .

Article Snippet: In ALLFTD, plasma NfL concentrations were measured using the Simoa NF-Light digital immunoassay (Quanterix, Cat. No. 103186), and plasma GFAP using the Simoa GFAP digital immunoassay (Quanterix, Cat. No. 102336, Lot 503909), both on the HD-X Analyzer.

Techniques: Clinical Proteomics, Variant Assay